Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis (IPF/Oxymizer2)

Klaus Kenn

Status

Completed

Conditions

Idiopathic Pulmonary Fibrosis

Hypoxemia

Treatments

Device: conventional nasal cannula

Device: Oxymizer® pendant nasal cannula

Study type

Interventional

Funder types

Other

Identifiers

NCT03411876

IPF Oxymizer study II

Details and patient eligibility

About

Aim of this study is to investigate the effects of an Oxymizer pendant nasal cannula in hypoxemic patients with idiopathic pulmonary fibrosis during walking.

Full description

Patients will be recruited during an inpatient pulmonary rehabilitation program. They will perform three shuttle walk tests on three consecutive days (see below). While performing those tests, the patient's prescribed oxygen flow rate is applicated either through the conventional nasal cannula (CNC) or the Oxymizer.On the first day, patients perform an incremental shuttle walk test to determine maximum walking speed using a conventional nasal cannula.

On two consecutive days, patients will perform two endurance shuttle walk tests at 85% of the maximum incremental shuttle walk test speed. Supplemental oxygen will be provided via nasal cannula at the prescribed oxygen flow rate. Patients will be randomly assigned to perform one test with the Oxymizer and the other one with a conventional nasal cannula.

Enrollment

22 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

firmed diagnosis of idiopathic pulmonary fibrosis
indication for supplemental oxygen therapy during exercise
referred to an inpatient rehabilitation program at the Schön Klinik Berchtesgadener Land

Exclusion criteria

cardiovascular diseases that influence the patient's physical performance
orthopedic comorbidities that prevent the patient from performing an incremental or endurance shuttle walk test
carbon dioxide pressure above 45 mmHg at rest and ambient air

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

22 participants in 2 patient groups

First ESWT with Oxymizer, second ESWT with CNC

Experimental group

Description:

Patients in this study arm first perform the first endurance shuttle walk test (ESWT) with the Oxymizer and the second ESWT with a conventional nasal cannula (CNC).

Treatment:

Device: conventional nasal cannula

Device: Oxymizer® pendant nasal cannula

First ESWT with CNC, second ESWT with Oxymizer

Experimental group

Description:

Patients in this study arm first perform the first endurance shuttle walk test (ESWT) with the CNC and the second ESWT with the Oxymizer.

Treatment:

Device: conventional nasal cannula

Device: Oxymizer® pendant nasal cannula