Effects of Oxytocin and Vasopressin on Moral Decision Making

University of Electronic Science and Technology of China

Status: Completed

Conditions: Healthy

Treatments: Drug: Oxytocin; Drug: Placebo; Drug: Vasopressin

Study type: Interventional

Funder types: Other

Identifiers

NCT04890470

UESTC-neuSCAN-78

Details and patient eligibility

About

To determine whether the neuropeptide oxytocin (OXT) and vassopressin (AVP) influence moral decision making

Full description

In a double-blind, between- subject placebo (PLC) controlled design, subjects will first complete a series of questionnaires in terms of mood, clinical symptoms, and traits. After that their moral judgment and emotion towards both verbal descriptions of moral dilemma scenarios and pictures of specific interpersonal ones will be assessed and the effect of intranasal OXT and AVP between both male and female healthy subjects will be investigated.

Enrollment: 180 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

• pregnancy

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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180 participants in 3 patient groups, including a placebo group

oxytocin group

Experimental group

Description:

subjects with oxytocin treatment

Treatment:

Drug: Oxytocin

vasopressin group

Experimental group

Description:

subjects with vasopressin treatment

Treatment:

Drug: Vasopressin

placebo group

Placebo Comparator group

Description:

subjects with placebo treatment

Treatment:

Drug: Placebo