Effects of Peppermint Oil in Cardiometabolic Outcomes

University of Central Lancashire

Status: Completed

Conditions: Cardiometabolic Syndrome

Treatments: Dietary Supplement: Peppermint oil.; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05071833

Peppermint oil cardiometabolic

Details and patient eligibility

About

Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount. Dietary interventions to improve cardiometabolic health are highly sought after as they possess less risk than pharmacological drugs. Previous non-randomized interventions have shown that oral peppermint may be beneficial in improving cardiometabolic outcomes. However, to date, no research has explored this using a placebo randomized intervention.

Therefore, the primary purpose of the proposed investigation is to test the ability of oral peppermint oil supplementation to improve cardiometabolic parameters in healthy individuals.

Enrollment: 36 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Between 18 & 65 years
• Non-smoker
• BMI < 30
• Able to give informed consent

Exclusion criteria

• Pregnancy
• Diabetes or any other metabolic/ uncontrolled hypertensive conditions
• Food allergies to peppermint
• Habitual consumption of peppermint
• Not regularly taking medication or antioxidant supplements

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Identical in taste and colour to the supplement juice, but with no peppermint content.

Treatment:

Other: Placebo

Peppermint oil

Experimental group

Description:

50 uL of peppermint oil, which will be diluted with 100 mL of water - taken twice per day.

Treatment:

Dietary Supplement: Peppermint oil.