Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty

Umraniye Education and Research Hospital

Status: Enrolling

Conditions: Postoperative Pain, Acute; Analgesia

Treatments: Procedure: Pericapsular Nerve Group (PENG) Block

Study type: Interventional

Funder types: Other

Identifiers

NCT06183528

UERH-AR-ZT-02

Details and patient eligibility

About

The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier mobilisation.

Full description

This prospective randomised controlled study included a total of 60 patients aged 40-85 years who underwent THA surgery under spinal anaesthesia. Patients were divided into two groups as PENG block (n:30) and non-PENG block (n:30). PENG block was placed in the fascial plane between the pseudotendon and pubic ramus with USG in-plane technique, 20 ml of 0.5% bupivacaine was administered and surgery was initiated. The primary outcome of the study was to investigate the effect of preoperative PENG block application on postoperative pain, opioid requirement, mobilisation time, hip joint patency and length of hospital stay in patients undergoing THA surgery. The secondary outcome was to investigate the effect of PENG block on perioperative haemodynamics and postoperative side effects.

For multimodal analgesia, 10 ml 0.5% bupivacaine + 10 ml 2% lidocaine is infiltrated into the surgical wound incision line by the surgical team at the end of surgery. After tramadol 50 mg loading with PCA device, a basal rate of 5-10 mg/hour (20 mg bolus dose + 30 minutes lock time) is given with paracetamol 10 mg/kg iv (8 hours interval).

Enrollment: 60 estimated patients

Sex: All

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• THA performed by posterior approach
• 40-85 age range
• ASA 1-3

Exclusion criteria

Under 40 years of age, over 85 years of age,

• ASA 4 and above,
• Cognitive impairment (Alzheimer's disease, dementia, delirium etc.),
• Hip fracture,
• Application site infection,
• Allergy to local anaesthetic agents,
• Patients are non-consenting patients.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

60 participants in 2 patient groups, including a placebo group

PENG group

Active Comparator group

Description:

PENG block was placed in the fascial plane between the pseudotendon and pubic ramus with USG in-plane technique, 20 ml of 0.5% bupivacaine was administered after spinal anaesthesia.

Treatment:

Procedure: Pericapsular Nerve Group (PENG) Block

non-PENG group

Placebo Comparator group

Description:

group non-PENG, surgery was started without PENG block after spinal anaesthesia.

Treatment:

Procedure: Pericapsular Nerve Group (PENG) Block