Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Bispebjerg Hospital

Status: Completed

Conditions: Patellar Tendinopathy / Jumpers Knee

Treatments: Procedure: heavy slow resistance training; Procedure: peritendinous corticosteroid injections; Procedure: eccentric decline squat training

Study type: Interventional

Funder types: Other

Identifiers

NCT00404469

Patellar tendinopathy

Details and patient eligibility

About

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Full description

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Enrollment: 39 patients

Sex: Male

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical patellar tendinopathy pain.
• Tendon swelling
• Hypoechoic
• Doppler activity in tendon

Exclusion criteria

• Previous knee surgery
• diabetes
• arthritis
• previous steroid injections

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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39 participants in 3 patient groups

CORT

Active Comparator group

Description:

Peritendinous corticosteroid injections at 0 and 4 weeks. 12 weeks total

Treatment:

Procedure: peritendinous corticosteroid injections

ECC

Experimental group

Description:

12 weeks of eccentric unilateral decline squats

Treatment:

Procedure: eccentric decline squat training

HSR

Experimental group

Description:

Heavy slow resistance training. 3/week. 12 weeks

Treatment:

Procedure: heavy slow resistance training