Effects of Phototherapy by Low-level Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical, Biomechanical, Histologic and Genetic Responses of Muscle Performance of Young Males Submitted to Physical Strength Training

Universidade Federal de Sao Carlos

Status: Completed

Conditions: Healthy

Treatments: Device: Effective light-emitting diode therapy; Device: Placebo light-emitting diode therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01770938

CAAE: 0326.0.135.000-11

Details and patient eligibility

About

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, light-emitting diode therapy (LEDT) has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations in gene expression of muscle tissue as well as biochemical, biomechanic and histologic adaptations influenced by exercise associated to LEDT.

Full description

This study assessed muscle performance in isokinetic dynamometry and led press device, gene expression by RT-PCR, lactate, creatine kinase and morphology of muscle tissue by immunohistochemical analysis

Enrollment: 32 patients

Sex: Male

Ages: 18 to 28 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy males aged between 18 and 28 years with a body mass index (BMI) equal to or less than 26 kg/m2,
• moderated pattern of physical activity

Exclusion criteria

• previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
• osseous or articular disorder in the lower limbs,
• cardiovascular system disorders,
• systemic disease, and
• taking prescription medicines or using dietary supplements such as muscle mass builders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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32 participants in 2 patient groups, including a placebo group

Effective light-emitting diode therapy and training

Active Comparator group

Description:

Effects of effective light-emitting diode therapy therapy on muscle performance of young males submitted to physical strength training

Treatment:

Device: Effective light-emitting diode therapy

Placebo light-emitting diode therapy and training

Placebo Comparator group

Description:

Effects of placebo light-emitting diode therapy on muscle performance of young males submitted to physical strength training

Treatment:

Device: Placebo light-emitting diode therapy