Effects of Physical-Cognitive Training With Different Task Models in Parkinson's Disease With Mild Cognitive Impairment

National Taiwan University

Status: Completed

Conditions: Mild Cognitive Impairment; Parkinson Disease

Treatments: Behavioral: Consecutive physical-cognitive training; Behavioral: Integrated physical-cognitive training

Study type: Interventional

Funder types: Other

Identifiers

NCT05172661

202109095RINA

Details and patient eligibility

About

The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.

Enrollment: 27 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a diagnosis of idiopathic Parkinson's disease
• have decreased cognitive functions but do not interfere with functional independence
• Montreal Cognitive Assessment (MoCA): 21-25
• able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°

Exclusion criteria

• a diagnosis of dementia
• other diseases that may influence cognitive functions or walking performance
• a history of brain surgery
• modification of the medication during the exercise intervention

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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27 participants in 2 patient groups

Integrated training model

Experimental group

Description:

Participants in this group will accept postural and cognitive training at the same time, e.g. naming animals while standing on the foam. Each training session will last for 70 minutes, twice a week, and 12 sessions in total.

Treatment:

Behavioral: Integrated physical-cognitive training

Consecutive training model

Experimental group

Description:

Participants in this group will accept postural and cognitive training separately and for identical durations (both 30 minutes). Each training session will last for 70 minutes, twice a week, and 12 sessions in total.

Treatment:

Behavioral: Consecutive physical-cognitive training