Effects of Physical Exercise in Type 2 Diabetics

University Hospital, Strasbourg, France

Status: Terminated

Conditions: Type 2 Diabetes Mellitus

Treatments: Behavioral: Physical exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01095068

3661

Details and patient eligibility

About

The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.

Enrollment: 15 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• sedentary adult with type 2 diabetes
• BMI between 25 and 35 kg/m²
• Hba1c < 10 %

Exclusion criteria

• unstable coronary artery disease
• advanced peripheral occlusive arterial disease
• proteinuria > 3 g/d and / or creatinine clearance < 30 ml / mn
• advanced diabetic neuropathy

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

15 participants in 1 patient group

physical exercise

Experimental group

Description:

Physical exercise

Treatment:

Behavioral: Physical exercise