Effects of Pilates Exercises in Asthmatic Patients

University of Sao Paulo General Hospital

Status: Unknown

Conditions: Asthma

Treatments: Other: Pilates; Other: Muscle stretching

Study type: Interventional

Funder types: Other

Identifiers

NCT03670654

EPEAP

Details and patient eligibility

About

Asthma is a chronic respiratory disease with high prevalence worldwide, considered an important cause of morbidity, mortality and high economic costs. Aerobic physical exercise has great merit as non-pharmacological treatment and other exercise modalities have being studied. However, there are few data in the literature about the effects of Pilates method in patients with asthma. The objective of this study is evaluate the effects of a program of exercise using Pilates on health factors related to quality of life in patients with moderate or severe persistent asthma. Patients will be also evaluated about disease control, anxiety and depression symptoms, functional capacity, lung function, respiratory muscle strength, thoracoabdominal mechanics and level of daily life physical activity. The investigators' hypothesis is that strengthening of the deep trunk muscles promotes a mechanical fixation of the thorax, contributing to the clinical improvement of patients with asthma.

Full description

This is a randomized, controlled and single blinded trial. Thirty adults with moderate or severe persistent asthma will be randomly assigned into two groups: Pilates method - PM (training group) or muscle stretching exercises - MSE (control group). All subjects will receive the same educational session and will perform the physical exercise proposed for the group for 12 weeks, 3 times/week, 40-minute sessions. The data normality will be analyzed by Kolmogorov-Smirnov, the variables obtained before interventions will be compared with the Student t-test or Mann-Whitney U-test. Comparisons of the initial and final data on outcomes will be analyzed with repeated measures ANOVA with appropriate post hoc of Holm-Sidak. The significance level will be set to 5% for all tests.

Enrollment: 30 patients

Sex: All

Ages: 20 to 59 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Asthma moderate and severe
• Asthma will diagnosed (Global Initiative for Asthma -GINA)
• Asthma medication according recommendations from GINA
• Body Mass Index ≥18.5 kg/m2 and <35 kg/m2
• Sedentary
• Medical treatment, for at least 6 months
• Clinically stable (i.e., no exacerbation or medication changes for at least 30 days)

Exclusion criteria

• Current or ex-smokers (who have given up smoking less than 1 year and/or tobacco charge greater than 10 pack-years)
• Cardiovascular, musculoskeletal and other chronic lung diseases
• Pregnant
• Active cancer
• Uncontrolled hypertension or diabetes
• Continuous use of oral corticosteroid
• Psychiatric disease or cognitive deficit

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

30 participants in 2 patient groups

Pilates Method

Active Comparator group

Description:

The intervention of active comparator will be Pilates Method exercises.

Treatment:

Other: Pilates

Muscle stretching exercises

Sham Comparator group

Description:

The intervention of sham comparator will be muscle stretching exercises.

Treatment:

Other: Muscle stretching