Effects of Plasmapheresis on Aging Biomarkers

Charles University, Czech Republic

Status: Completed

Conditions: Plasmapheresis; Aging

Treatments: Procedure: Plasmapheresis

Study type: Observational

Funder types: Other

Identifiers

NCT05004220

202103 P07

Details and patient eligibility

About

The aim of the study is to evaluate the effect of plasmapheresis (repeated plasma withdrawals) on selected health indicators (hematological, biochemical, immunological and indicators of biological age) of plasma donors.

Enrollment: 41 patients

Sex: All

Ages: 40 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Generally healthy volunteer subjects age 40 - 60
2. 50:50 man and woman

Exclusion criteria

1. Subjects excluded from plasma donation protocols (serious illness, infection, etc)
2. Subjects undergoing stronger anti-aging interventions

Trial design

41 participants in 2 patient groups

Group 1

Description:

Group 1 consists of first time donors undergoing all 8 tracked plasmaphereses.

Treatment:

Procedure: Plasmapheresis

Group 2

Description:

Group 2 consists of first time donors undergoing only last 4 plasmaphereses, serving as control for the first 4 donations.

Treatment:

Procedure: Plasmapheresis