Effects of Preoperative Rehabilitation in Patients Resected for Lung Cancer (Rexochir)

Centre Jean Perrin

Status: Active, not recruiting

Conditions: Lungcancer

Treatments: Other: preoperative rehabilitation program; Other: preoperative chest physiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03020251

2016-A00622-49

Details and patient eligibility

About

This randomized controlled trial will evaluate the effect of a preoperative rehabilitation program at home in patients resected for lung cancer, comparing a control group (C group) receiving only chest physiotherapy and a rehabilitation group (R group) receiving both a training program at home and chest physiotherapy

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed for lung cancer (or highly suspicious for cancer tumor) eligible for resection surgery (lobectomy or pneumonectomy)
• Age > 18 years
• Presence of Chronic Obstructive Pulmonary Disease (COPD) stages 2-4 of Gold (forced expiratory volume (FEV )/ forced vital capacity (FVC) <70%, FEV <80% of predicted) and Exertional dyspnea stage MMRC (Medical Research Council) > 1
• Patients must provide written consent
• Member of social security scheme

Exclusion criteria

• Patients refusing to participate
• COPD stage 1 Gold (VEMS >= 80% of the theoretical value)
• Presenting an operating contraindication during the initial maximal exercise test
• Presenting cardiac or vascular contraindication to achieve the readaptation program
• Patient living alone at home
• Patient with ventilatory assistance at home (oxygen therapy or noninvasive ventilation (NIV))
• With exercise hypoventilation (PaCO2 >45 mmHg)
• Cognitive difficulty
• unable major
• pregnancy,
• patients deprived of liberty by a court or administrative decision

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

control group (C group)

Active Comparator group

Description:

patient will receive preoperative chest physiotherapy (standard supportive care)

Treatment:

Other: preoperative chest physiotherapy

rehabilitation group (R group)

Experimental group

Description:

patient will receive preoperative chest physiotherapy and a preoperative rehabilitation program at home (exercise training)

Treatment:

Other: preoperative chest physiotherapy

Other: preoperative rehabilitation program