Effects of Probiotic and HIIT in Obese Women

University of Taipei

Status: Completed

Conditions: Metabolism; Anthropometry; Cardiorespiratory Fitness

Treatments: Dietary Supplement: Placebo supplementation; Dietary Supplement: Probiotics supplementation; Behavioral: HIIT training

Study type: Interventional

Funder types: Other

Identifiers

NCT06285578

MOST 107-2410-H-277-003

Details and patient eligibility

About

The aim of this study is to investigate whether there are the additive effects when implementing both high-intensity interval training (HIIT) and probiotics simultaneously on improving cardiorespiratory endurance and metabolism in middle-aged women.

Full description

High-intensity interval training (HIIT) is a time-efficiency exercise mode that has been shown to reduce body fat, fasting blood insulin levels, arterial stiffness, and aerobic capacity, helping to prevent and improve chronic diseases. Probiotics, on the other hand, have been found to have similar effects, including improving insulin sensitivity and endurance exercise performance, as well as reducing body fat. However, the additive effects of HIIT combined with probiotic supplements are unclear. In addition, on average, the life expectancy of women is longer than that of men. Middle-aged women are at high-risk for obesity and metabolic-related problems that threaten their long-term health. Therefore, whether the combination of HIIT and probiotics can be utilized to enhance the wellness of middle-aged women is the objective of this study.

Enrollment: 47 patients

Sex: Female

Ages: 35 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female
• Age between 35-55 years old
• Total body fat percentage greater than 30%

Exclusion criteria

• Male
• Participants who were taking probiotics supplementation or antibiotics
• Percentage of total body fat less than 30%

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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47 participants in 4 patient groups, including a placebo group

Placebo control (C)

Placebo Comparator group

Description:

The subjects do not perform HIIT training, but consume one placebo packet every day on a fasting status for 8 weeks.

Treatment:

Dietary Supplement: Placebo supplementation

Probiotics supplementation (P)

Experimental group

Description:

Each participant consume one probiotic packet every day on a fasting status for 8 weeks.

Treatment:

Dietary Supplement: Probiotics supplementation

HIIT intervention (H)

Experimental group

Description:

HIIT training for 3 sessions per week and consume one placebo packet every day on a fasting status for 8 weeks.

Treatment:

Dietary Supplement: Placebo supplementation

Behavioral: HIIT training

HIIT with probiotics intervention (HP)

Experimental group

Description:

Conduct HIIT training 3 sessions per week for 8 weeks and consume one probiotic packet every day on a fasting status for 8 weeks.

Treatment:

Dietary Supplement: Probiotics supplementation

Behavioral: HIIT training