Effects of Progressive Elastic Band Resistance Training

Buddhist Tzu Chi Medical Foundation

Status: Completed

Conditions: Prader-Willi Syndrome; Resistance Training

Treatments: Device: PWS elastic band training group

Study type: Interventional

Funder types: Other

Identifiers

NCT03565081

04-XD33-100

Details and patient eligibility

About

Abnormal body composition with increased body fat mass and decreased lean body mass has been found in adults with Prader-Willi syndrome (PWS), contributing to reduced physical capacity and impairment. The aim of this study was to investigate whether progressive elastic band resistance training can improve physical motor performance and regional body composition in adults with PWS.

Full description

Six participants were enrolled in this pilot study. Following 24 weeks of progressive elastic band resistance exercise training, significant reduction was observed in their body weight, BMI, and regional extremities fat mass and percentage. Regarding the functional performances, there were also significant improvements in their hand grip strength, 3 meter timed up and go, 30 seconds sit to stand, and 2-min step up tests, as early as the 8th week of training. Balance function achieved significant improvements after 16 weeks of training.

Enrollment: 6 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PWS individuals who can cooperate with motor performances

Exclusion criteria

• arthritis, fracture, or severe musculoskeletal deformities that would interfere with exercise training or motor performance
• severe cognitive impairment or parents who cannot read nor write.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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6 participants in 1 patient group

PWS elastic band training group

Experimental group

Description:

Genetically confirmed diagnosis of PWS participants were recruited. The PWS participants needed to have sufficient command of the Mandarin language to understand the study information and motivated to conduct the training program.

Treatment:

Device: PWS elastic band training group