Effects of Propofol-Induced Anaesthesia on the ST-segment of the ECG (Prop ST)

Universitair Ziekenhuis Brussel

Status: Unknown

Conditions: No Specific Condition (Patients Without Brugada Syndrome)

Treatments: Other: Observational study

Study type: Observational

Funder types: Other

Identifiers

NCT05185401

Prop ST-Segment

Details and patient eligibility

About

The purpose of this study is to assess the effect of propofol induced general anaesthesia on the ST-segment of the electrocardiogram. This will be realised by retrospectively analysing the ECG-recordings from adult patients undergoing any treatment at the Catheterisation Laboratory. The ST-segment and other ECG measurements from induction of anaesthesia up to 20 minutes later, will be assessed and compared to the baseline values of the respective segments acquired before injecting propofol. It is essential in this study to exclude any patients burdened with the diagnosis, suspicion or family history of Brugada syndrome.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Induction of anaesthesia with propofol
• Monitored anaesthesia in the CathLab of the Universitair Ziekenhuis Brussel

Exclusion criteria

• Brugada Syndrome or family history of Brugada syndrome
• Paediatric population (age <18)
• Patients who did not receive propofol during the procedure
• Patients who presented with fever (central core temperature >38,0°C)

Trial design

500 participants in 1 patient group

non-Brugada population

Description:

Adult patients who underwent general anaesthesia (with propofol as induction agent) at the catheterisation laboratory of the UZ Brussel

Treatment:

Other: Observational study