Effects of Pulmonary Rehabilitation on Cognitive Function in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease

ADIR Association

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Other: Pulmonary rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT03244137

PR-COPD

Details and patient eligibility

About

Chronic obstructive pulmonary disease is a leading cause of mortality worldwide.

It is a systemic disease which includes pulmonary, cardiac, muscular, digestive and cognitive impairments.

Pulmonary rehabilitation is a symptomatic treatment to reduce dyspnea and functional incapacity. However, it effects on cognitive dysfunction are not well known.

The aim of this study is to assess the effects of a comprehensive pulmonary rehabilitation program on cognitive dysfunction in patients with severe to very severe chronic obstructive pulmonary disease using the Montreal Cognitive Assessment tool.

Enrollment: 56 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18years;
• Chronic obstructive pulmonary disease stade III to IV;
• Referred for pulmonary rehabilitation.

Non Inclusion Criteria:

• Pregnancy or likely to be;
• History of psychiatric, neuro-vascular, cognitive disease or cranial trauma;
• Active alcoholism;
• Guardianship;
• Hospitalisation for acute exacerbation of chronic obstructive pulmonary disease in the previous 4 weeks;

Exclusion criteria

• Interruption of the pulmonary rehabilitation program > 15 days;
• Disruption of the training before the 18th session;
• Less than 18 sessions in four month.

Trial design

56 participants in 1 patient group

Pulmonary rehabilitation

Description:

The whole population will benefit from a comprehensive pulmonary rehabilitation program, including aerobic training, superior and inferior limb strength training, self-management and add-on to pulmonary rehabilitation as needed (i.e : electrical muscle stimulation, inspiratory muscle training, non-invasive ventilation, high flow nasal canula).

Treatment:

Other: Pulmonary rehabilitation