Effects of Pulmonary Resection on Right Ventricular Function

Çağrı Özdemir

Status: Enrolling

Conditions: Pulmonary Resection; Echocardiography; Right Ventricular Function; Cardiothoracic Anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT07042893

2024 - 1160

Details and patient eligibility

About

Lung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications. One of the contributing factors to this functional decline is the postoperative reduction in right ventricular function. Due to the anatomical proximity and interactions, right ventricular function is evaluated by echocardiography following lung resection. The pulmonary artery pressure (PAP)/tricuspid annular plane systolic excursion (TAPSE) ratio is a parameter that provides a more comprehensive assessment of right heart function by evaluating both right ventricular systolic function and pulmonary artery pressure. In this study, investigators aimed to evaluate changes in right heart function by performing preoperative and postoperative echocardiographic assessments in participants undergoing lung resection, focusing on PAP/TAPSE ratios.

Enrollment: 25 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Adults aged 18 to 80 years

ASA classification I-III

Patients scheduled to undergo lung resection in thoracic surgery

Exclusion criteria

Patients with arrhythmia

Patients using antiarrhythmic drugs

Patients with renal failure requiring hemodialysis

Patients with a history of previous lung surgery

Patients with valvular heart disease

Patients with a history of angina pectoris or myocardial infarction within the past month

Patients with FEV1/FVC ratio below 60%

Trial design

25 participants in 1 patient group

Group 1

Description:

In this study, a single group (Group 1) will be defined, and patients scheduled for lung resection who agree to participate will be included.