Effects of Recruitment Maneuver During Intraoperative Period

Balikesir University

Status: Completed

Conditions: Laparoscopic Hysterectomy

Treatments: Procedure: PEEP; Procedure: Alveolar Recruitment maneuver (ARM) +PEEP

Study type: Interventional

Funder types: Other

Identifiers

NCT04239547

osagir-4

Details and patient eligibility

About

The aim of this study is to observe the effect of respiratory recruitment maneuver on intraoperative ventilatory parameters and postoperative pulmonary complications in patients over 18 years scheduled for laparoscopic hysterectomy.

Full description

In patients over 18 years who are scheduled for laparoscopic hysterectomy volunteering to participate in our study will receive anesthesia induction with one of our standard general anesthesia protocols. After intubation recruitment maneuver will be applied to the study group. General anesthesia and mechanical ventilation will be continued and completed according to our standard practice without any further intervention. Throughout the intraoperative period respiratory and haemodynamic parameters including compliance, airway resistance, mean arterial pressure, heart rate, pulse oxymetry, blood gas analysis, the applied inhalational anesthetic agent, minimum alveolar concentration, expiratory agent concentration and total agent consumption will be recorded. At the end of the operation anesthesia will be terminated and patients will be transferred to postanesthesia care unit (recovery unit after recovery and further discharged from to the ward when their Aldrete score is >8. The patients will be examined for respiratory complications on postoperative day 1, and will be followed up by telephone on day 5.

Enrollment: 80 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiology (ASA) I-II
• > 18 y
• laparoscopic hysterectomy patients

Exclusion criteria

• Patient refusal to participate in the study
• <18 y, BMI> 40
• Patients receiving invasive MV support in the last 1 month
• Patients who received chemotherapy or radiotherapy in the last 2 months
• Patients with severe pulmonary disease (COPD, asthma, pulm infection, bronchiectasis) (those who have previously received Non-Invasive MV, oxygen therapy or steroid therapy for an acute attack)
• Those with known severe pulmonary Hypertension
• Intracranial tm
• Hemodynamic instability
• Shock.
• Neuromuscular disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups

Recruitment

Experimental group

Description:

Patients classified to receive recruitment maneuver + 5 mmHg positive end-expiratory pressure after anesthesia induction and intubation.

Treatment:

Procedure: Alveolar Recruitment maneuver (ARM) +PEEP

Non-recruitment

Experimental group

Description:

Patients classified to receive only 5 mmHg positive end-expiratory pressure after anesthesia induction and intubation.

Treatment:

Procedure: PEEP