Effects of Rehabilitation Combined With a Maintenance Program Compared to Rehabilitation Alone in Post-COVID-19 (ReLoAd2)

Schön Klinik Berchtesgadener Land

Status: Enrolling

Conditions: Post-COVID-19 Syndrome

Treatments: Procedure: Rehabilitation without maintenance program; Procedure: Rehabilitation combined to a digital maintenance program

Study type: Interventional

Funder types: Other

Identifiers

NCT06124625

Reload 2.0

Details and patient eligibility

About

Infection with SARS-CoV-2 virus leads to persistent symptoms for more than 12 weeks in 15% of cases ("post-COVID syndrome"). Symptoms like fatigue, dyspnoea, limitations in physical performance and activities, head ache, anxiety symptoms, and depression are heterogenous which limit physical health and participation in daily life activities.

In the last years, multidisciplinary rehabilitation programs showed benefits in quality of life and symptom intensity in patients with post-COVID. Therefore, rehabilitation programs are recommended for individuals with Post-COVID by official sites like the German Society of Pulmonology and the European Respiratory Society.

Own first data (published at the ERS conference 2023) revealed that one the one hand, inpatient rehabilitation is effective, however, on the other hand, it is challenging to maintain these effects after completing the program. Therefore, the aim of this study is to sustain these benefits by using a digital maintenance program following the rehabilitation program compared to usual care.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Post-COVID-syndrome (Definition WHO)
• Entered the rehabilitation process at the Schoen Klinik Berchtesgadener Land

Exclusion criteria

• No internet access

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 2 patient groups, including a placebo group

Rehabilitation maintenance program

Active Comparator group

Treatment:

Procedure: Rehabilitation combined to a digital maintenance program

No Rehabilitation maintenance program

Placebo Comparator group

Treatment:

Procedure: Rehabilitation without maintenance program