Effects of Rehabilitation on Muscle Fibre Composition and Capillaries in Chronic Obstructive Pulmonary Disease (COPD) Patients

Schön Klinik Berchtesgadener Land

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Other: pulmonary rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT01715337

COPD muscle 2011

Details and patient eligibility

About

Pulmonary rehabilitation has been established as an evidence-based and recommended therapy in patients with chronic obstructive pulmonary disease (COPD). The aim of our study is to show a potential change in muscle fibre composition and in the amount of capillaries in quadriceps muscle from pre tob post 3-week rehabilitation. Pulmonary rehabilitation includes standardised exercise training, e.g. cycling and strength training for major muscle groups.

Enrollment: 20 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• chronic obstructive pulmonary disease
• FEV1%pred. < 50%

Exclusion criteria

• acute exacerbation
• exacerbation in the last 4 weeks

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

pulmonary rehabilitation

Other group

Treatment:

Other: pulmonary rehabilitation