Effects of Repeated Memory Training on Memory Function and Addiction Related Processes

Johns Hopkins University

Status: Terminated

Conditions: Substance-Related Disorders

Treatments: Behavioral: Comparator memory training 2; Behavioral: Experimental memory training; Behavioral: Comparator memory training 1

Study type: Interventional

Funder types: Other

Identifiers

NCT03285256

IRB00138474

Details and patient eligibility

About

Prospective memory is the ability to implement an intention to the future (e.g. remember to take medication, attend a scheduled meeting), and has receive little attention in addiction. The investigators propose that prospective memory plays a critical, yet unrecognized, role in major human behavior change such as that required in addiction treatment. This study will determine the preliminary efficacy of prospective memory training in improving memory and executive functions while reducing illicit drug use in methadone patients. Participants will be randomly assigned to one of three conditions: an experimental memory training program or one of two comparator memory training programs.

Enrollment: 1 patient

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-55; provision of written consent
• Enrolled in a substance use treatment program
• Sex with ≥ 2 partners in the last 30 days and sex without a condom on at least one occasion in the last year

Exclusion criteria

• Severe psychiatric conditions associated with psychosis or any unstable psychiatric condition
• History of medical, psychiatric, or neurological conditions associated with significant cognitive impairment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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1 participants in 3 patient groups

Experimental Memory Training

Experimental group

Description:

Experimental memory training program

Treatment:

Behavioral: Experimental memory training

Comparator Memory Training 1

Active Comparator group

Description:

Comparator memory training program

Treatment:

Behavioral: Comparator memory training 1

Comparator Memory Training 2

Active Comparator group

Description:

Alternative comparator memory training program

Treatment:

Behavioral: Comparator memory training 2