Effects of Resistance and Endurance Training in Pediatric Cancer Patients During Intensive Treatment Phase (MUCKI)

Johannes Gutenberg University (JGU)

Status: Completed

Conditions: Pediatric Oncology

Treatments: Behavioral: Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT02612025

Mucki01

Details and patient eligibility

About

The purpose of this study is to determine whether combined endurance and resistance training can improve muscle strength in children and adolescents with cancer during the intensive treatment phase.

Enrollment: 35 patients

Sex: All

Ages: 4 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Malignant Tumor
• Medical Treatment in the Center for Pediatrics, Hematology, Oncology and Hemostaseology Mainz (Germany)
• > 3 years
• Signed Informed Consent

Exclusion criteria

• Functional and/or cognitive limitations which limit performance during training
• Orthopedic condition which hinders to adequately participate in exercise training
• Heart failure (NYHA III-IV)
• Partial or global respiratory failure
• Symptomatic coronary disease
• Serious therapy-refractory hypertonia
• Sustainable thrombocytopenia <10.000/µl, f. ex. therapy-refractory autoimmune thrombocytopenia
• Hereditary or acquired thrombocytopenia or coagulation disturbance
• Uncontrolled cerebral spasm
• CNS metastases
• Medical or psychological condition which does in the doctors opinion not allow participation in sport activity

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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35 participants in 2 patient groups

Exercise group

Experimental group

Description:

Exercise training during intensive medical treatment

Treatment:

Behavioral: Exercise Training

Control group

No Intervention group

Description:

Usual Care