Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults

University of Regina

Status: Enrolling

Conditions: Aging

Treatments: Dietary Supplement: Creatine Intermittent 5; Dietary Supplement: Placebo; Dietary Supplement: Creatine Bolus 3; Dietary Supplement: Creatine Bolus 5

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT06606704

853

Details and patient eligibility

About

The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

Full description

Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.

Creatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.

Evidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.

Enrollment: 52 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• if you are 50 years of age and older
• if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.

Exclusion criteria

• if you have taken creatine supplements within 30 days prior to the start of the study
• if you have pre-existing allergies to the placebo (corn-starch maltodextrin).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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52 participants in 4 patient groups, including a placebo group

Creatine Bolus 5

Experimental group

Treatment:

Dietary Supplement: Creatine Bolus 5

Creatine Bolus 3

Experimental group

Treatment:

Dietary Supplement: Creatine Bolus 3

Creatine Intermittent 5

Experimental group

Treatment:

Dietary Supplement: Creatine Intermittent 5

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo