Effects of Respiratory Muscle Exercises on Glucose Tolerance in Healthy Adults

Federal Institute of Technology (ETH) Zurich

Status: Completed

Conditions: Healthy Diet; Healthy Aging

Treatments: Other: 15min respiratory muscle exercises; Other: 5min respiratory muscle exercises

Study type: Interventional

Funder types: Other

Identifiers

NCT04520763

HOGTT_2020

Details and patient eligibility

About

To evaluate the acute effects of respiratory muscle exercises vs. a control intervention on blood glucose kinetics in healthy adults after an oral glucose tolerance test.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Healthy
• Non-smoking
• Body mass index (BMI): 18.5 - 29.9 kg∙m-2
• Normal lung function
• Willing to adhere to study rules

Exclusion criteria

• Known or suspected non-compliance, drug or alcohol abuse
• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant
• Previous enrolment into the current study
• Intake of medications affecting metabolism, the cardiovascular or the respiratory system, or sleep
• Acute illness or chronic conditions of the gastrointestinal tract, and health conditions affecting metabolism, the cardiovascular or the respiratory system, or sleep
• Pregnancy, breastfeeding, or intention to become pregnant during the study

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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42 participants in 2 patient groups

Respiratory Muscle Exercises

Experimental group

Description:

Two respiratory muscle exercises

Treatment:

Other: 5min respiratory muscle exercises

Other: 15min respiratory muscle exercises

Control

No Intervention group

Description:

The control intervention consists of quiet sitting for 15 min