Effects of RF Microneedle on Photoaging Skin

Ajou University School of Medicine

Status: Completed

Conditions: Pigmentation Disorder; Pigmentation

Treatments: Drug: Combination cream; Device: RF Microneedle

Study type: Interventional

Funder types: Other

Identifiers

NCT05710068

AJOUIRB-INT-2021-133

Details and patient eligibility

About

Melasma relapse is almost common after discontinuation of conventional treatment. Recent studies have suggested that photoaging dermis is main pathomechanism of melasma emphasizing stromal targeting therapy. Therefore, we investigated maintenance effect of microneedle radiofrequency (RF) for melasma treatment.

Enrollment: 15 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult more than 19 years old
• Melasma clinically diagnosed by three dermatologists

Exclusion criteria

• Aesthetic medical procedures in three months prior to the study
• Use of topical depigmenting agents in three months prior to the study
• Pregnant or lactating

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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15 participants in 2 patient groups

Conventional therapy with RF microneedle

Experimental group

Description:

Half face Oral tranexamic acid combined with triple combination cream with RF microneedle

Treatment:

Drug: Combination cream

Device: RF Microneedle

Conventional therapy

Active Comparator group

Description:

Half face Oral tranexamic acid combined with triple combination cream

Treatment:

Drug: Combination cream