Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne

Shahid Beheshti University of Medical Sciences

Status and phase: Completed; Phase 1

Conditions: Acne

Treatments: Drug: isotretinoin (Roaccutane)

Study type: Interventional

Funder types: Other

Identifiers

NCT00416585

src-hmnm-1385

Details and patient eligibility

About

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

Full description

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• sever acne

Exclusion criteria

• renal disorders
• gastrointestinal disorders
• skeletal disorders
• endocrine disorders
• drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)