Effects of Short-intensity Modified Constraint-induced Movement Therapy on Hand Function in Stroke Patients.

Riphah International University

Status: Completed

Conditions: Rehabilitation; Ischemic Stroke; Hemorrhagic Stroke

Treatments: Other: short-intensity modified CIMT and conventional therapy; Other: conventional therapy alone

Study type: Interventional

Funder types: Other

Identifiers

NCT05916885

REC/RCR & AHS/23/0213

Details and patient eligibility

About

To determine effects of short-intensity modified constraint-induced movement therapy on hand function in stroke patients.

Full description

The aim of the study is to determine the effects of a short-intensity modified CIMT (mCIMT) program on hand function in stroke patients. This study will be a randomized controlled trial comprising two groups, an experimental group in which patients will be given short-intensity mCIMT along with conventional therapy. A control group, in which participants will be given conventional therapy alone. Patients will be assessed with the Wolf Motor Function Test, the Motor Activity Log, and the Ashworth Scale before and after treatment. The data will be analyzed by using SPSS for windows software version 25. Statistical significance will be set at p=0.05.

Enrollment: 38 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients having the First stroke either ischemic or hemorrhagic (3-24 months after stroke)
• Patients having Mini-mental status examination score (MMSE) ≤23/30
• Patients having Passive range of motion (PROM) includes at least 90 degrees shoulder flexion and abduction, 45degrees shoulder external rotation,- 30 degrees elbow extension, and 45 degrees forearm supination and pronation (from a neutral position). At least 10 degrees active wrist extension, 10 degrees abduction/thumb extension, and 10-degree extension at the level of the metacarpophalangeal and interphalangeal joints between the two toes among the II-III-IV-V fingers (these movements will be repeated starting from a resting position 3 times in 1 minute).

Exclusion criteria

• Patients having Subarachnoid hemorrhage.
• Patients having Motor activity log - the amount of use score ≥2.5
• Patients having treatment of upper limb spasticity (e.g., botulinum toxin) in the 3 months prior to the start of the study and/or during its execution.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

38 participants in 2 patient groups

experimental group

Experimental group

Description:

an experimental group receiving short-intensity modified CIMT and conventional therapy

Treatment:

Other: short-intensity modified CIMT and conventional therapy

control group

Active Comparator group

Description:

a control group receiving conventional therapy alone.

Treatment:

Other: conventional therapy alone