Effects of Smoking Environment on Craving and Smoking (CC2pilot)

Duke University

Status

Completed

Conditions

Smoking

Treatments

Behavioral: Delay to Smoking Task (smoking cues)

Behavioral: Delay to Smoking Task (nonsmoking cues)

Behavioral: 6 hour smoking abstinence

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT02416986

Pro00056221

R01DA038442-01 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of this study is to evaluate the effects of exposure to standard smoking environments on ability to resist smoking as measured with a Delay to Smoking Task. The results of this study will inform whether the Delay to Smoking Task is a sensitive measure for evaluating environment-provoked craving and smoking behavior.

Full description

Adult smokers (n=25) will complete 4 visits and a 6 month follow-up phone call. Participants will complete a Delay to Smoking Task following 6 hours smoking abstinence. The task involves viewing pictures of smoking and non-smoking locations and participants will have the choice to smoke a cigarette at any time during the session. A monetary reinforcer will be provided for each 6-minute period that a participant resists smoking. Once participants stop the task they can choose to smoke as much or a little as they want for the next 30 minutes. Participants will be provided with a smoking tab. Each cigarette they light will cost them from their tab. Measurements of tobacco craving, emotion ratings, and nicotine withdrawal will be assessed.

Enrollment

41 patients

Sex

All

Ages

18 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

generally healthy
between the ages of 18 and 55
smoking an average of 5 cigarettes per day for at least one year
breath CO level > 8 ppm (if ≤ 8 ppm, then NicAlert Strip = 6)
no interest in quitting smoking for the duration of time required for the experiment

Exclusion criteria

inability to attend all required experimental sessions
use of psychoactive medications
use of smokeless tobacco
current alcohol or drug abuse
use of illegal drugs as measured by urine drug screen (excluding marijuana)
current use of nicotine replacement therapy or other smoking cessation treatment
Blood Alcohol Level (BAL) > 0.00
use of other tobacco products or e-cigarettes more than 9 days in the past 30 days