Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function

Centro Universitario La Salle

Status and phase: Enrolling; Phase 3

Conditions: Hypercapnia; Apnea; Hypoxia; Pain

Treatments: Other: Voluntary apnoea

Study type: Interventional

Funder types: Other

Identifiers

NCT06150677

CSEULS-PI-015/2023

Details and patient eligibility

About

The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent static apneas training session at high lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Asymptomatic subjects aged between 18 and 64 years.

Exclusion criteria

• Cardiovascular, respiratory, metabolic, neurological or osteomuscular signs or pathologies.
• History of epilepsy.
• Pregnant.
• Pharmacological treatment.
• Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 4 weeks.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Static apnea at High Lung Volume

Experimental group

Description:

Participants will remain at rest in the supine position for 6 minutes. Participants in the experimental group will perform intermittent apneas at high lung volume with a density of 30 seconds, followed by a normal breath of 10 seconds (9 cycles of 30s apnea - 10s normal breathing, until completing the 6 minutes).

Treatment:

Other: Voluntary apnoea

Static at normal breathing

No Intervention group

Description:

Participants will remain at rest in the supine position for 6 minutes. Participants in the control group will remain breathing normally for these 6 minutes