Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation

Mahidol University

Status: Invitation-only

Conditions: Radial Artery Cannulation

Treatments: Other: Normal saline; Drug: Nicardipine

Study type: Interventional

Funder types: Other

Identifiers

NCT05920538

764/2565(IRB3)

Details and patient eligibility

About

The goal of this study is to compare the success rate of subcutaneously infiltrated nicardipine to normal saline in radial artery cannulation

Enrollment: 190 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18-75 years
• the patient who need to arterial line

Exclusion criteria

• allergy to nicardipine
• history of peripheral artery disease
• BMI > 40 kg/m2
• unwilling to participate or denial of informed consent

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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190 participants in 2 patient groups, including a placebo group

Nicardipine

Experimental group

Description:

Using nicardipine 0.5 mg(0.5ml) subcutaneously infiltrated by ultrasound before redial artery cannulation.

Treatment:

Drug: Nicardipine

Normal saline

Placebo Comparator group

Description:

Using normal saline 0.5ml subcutaneously infiltrated by ultrasound before redial artery cannulation

Treatment:

Other: Normal saline