Effects of Sufentanil on the Intraoperative Hemodynamics

Seoul National University

Status: Enrolling

Conditions: Intraoperative Hypotension

Treatments: Drug: Sufentanil; Drug: Remifentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT06091904

Bypass-SFTN

Details and patient eligibility

About

This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.

Enrollment: 92 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who undergo elective extracranial-intracranial bypass surgery
• American Society of Anesthesiologists grade 1,2,3
• Age > 18 years old

Exclusion criteria

• Refuse to participate to the study
• American Society of Anesthesiologists grade 4
• Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
• Allergic history of opioid
• pregnant
• MAO Inhibitor user
• Severe respiratory insufficiency

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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92 participants in 2 patient groups

sufentanil group

Experimental group

Description:

sufentanil is administered for analgesic during general anesthesia

Treatment:

Drug: Sufentanil

remifentanil group

Active Comparator group

Description:

remifentanil is administered for analgesic during general anesthesia

Treatment:

Drug: Remifentanil