Effects of Supplementation With Ginseng and BCAA Improved Central Fatigue and Enhanced Attention During Exercise

TCI

Status: Completed

Conditions: Exercise Addiction

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Gojinsen® drinks

Study type: Interventional

Funder types: Industry

Identifiers

NCT05129917

TSMH No.13-023-A2

Details and patient eligibility

About

The main purpose of the present study is to determine the effects of acute and short-term (14 days) ginseng combined with branch chained amino acids supplementation on endurance exercise performance and the ability of anti-fatigue. In addition, this study also measured the performance of continuous attention during recovery period to examine the effect of supplementation on central fatigue.

Full description

Muscle fatigue was a common problem after exercise. When fatigue occured, body functions were affected and changed. Changbai Mountain ginseng had higher anti-fatigue substances than general commercial ginseng. And recent studies had showed that the supplementation of branched chain amino acids (BCAA), including leucine, isoleucine and valine, can increase attention and reduce fatigue. However, its effect on Changbai Mountain ginseng combined with BCAA was still unclear. Subjects were allocated to Gojinsen® drinks and placebo group (1:1 ratio) for 14 days, and then examined by maximal oxygen consumption, time to exhaustion, rating of perceived exertion (RPE), oxygen saturation (SPO2) , blood lactate concentration, and continuous attention performance test (CPT II). The Gojinsen® group significant increased maximal oxygen consumption, time to exhaustion, and attention compared to placebo group. Moreover, the Gojinsen® group significant decreased lactate concentration and fatigue compared to placebo group. By this study, Gojinsen® drinks did not showed absolute anti-fatigue effect but provided the objective evidence of fatigue-related measurement and the therapeutic potential for people suffering from exercise fatigue.

Enrollment: 16 patients

Sex: All

Ages: 20 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. healthy male and female adults aged 20-25 years old .
2. without heart, liver, kidney, endocrine or other major organic diseases).
3. had at least 3 months experience in performing exercise

Exclusion criteria

1. BMI of the study subjects must be less than 25.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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16 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

consume 1 sachet per day for 14 day

Treatment:

Dietary Supplement: Placebo

Gojinsen® drinks

Experimental group

Description:

consume 1 sachet per day for 14 day

Treatment:

Dietary Supplement: Gojinsen® drinks