Effects of Systemic Drugs on Intraocular Pressure

B

Benha University

Status

Enrolling

Conditions

Hypertension
Glaucoma Secondary to Drugs, Bilateral
Glaucoma Suspect
Glaucoma, Angle-Closure

Treatments

Drug: Antihistaminics
Drug: Antihypertensive Agents

Study type

Observational

Funder types

Other

Identifiers

NCT05328921
Rc 9-22

Details and patient eligibility

About

To assess intraocular pressure changes among glaucoma patients on systemic antihypertensive and antihistaminic drugs.

Full description

Changes in intraocular pressure in glaucomatous patients with narrow angle may elicit attacks of angle closure glaucoma. In this study we aim to assess changes in intraocular pressure (IOP) among glaucomatous patients on systemic antihypertensive and antihistaminic drugs.

Enrollment

200 estimated patients

Sex

All

Ages

35 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with narrow angle glaucoma on systemic antihypertensive and/or antihistaminic drugs.

Exclusion criteria

  • open angle glaucoma patients confirmed by gonioscopy examination.
  • Cases with dense corneal opacity or iris trauma that may affects gonioscopy examination.
  • cases with secondary glaucoma.

Trial design

200 participants in 3 patient groups

Antihypertensive drugs group
Description:
Changes in IOP among patients on antihypertensive drugs
Treatment:
Drug: Antihypertensive Agents
Antihistaminic drugs group
Description:
Changes in IOP among patients on antihistaminic drugs
Treatment:
Drug: Antihistaminics
Antihypertensive and antihistaminic drugs group
Description:
Changes in IOP among patients on both antihypertensive and antihistaminic drugs
Treatment:
Drug: Antihypertensive Agents
Drug: Antihistaminics

Trial contacts and locations

1

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Central trial contact

Marwa Abdelshafy, MD; Ahmed Abdelshafy, MD

Data sourced from clinicaltrials.gov

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