Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis

Bezmialem Vakif University

Status: Unknown

Conditions: Multiple Sclerosis, Relapsing-Remitting

Treatments: Other: Combined exercise training; Other: Task-oriented training

Study type: Interventional

Funder types: Other

Identifiers

NCT03497468

kunal

Details and patient eligibility

About

Multiple Sclerosis (MS) is inflammatory, demyelinating and autoimmune disease of the central nervous system. It is usually seen with relapses and genetic and environmental factors play a role in the etiology. Neurological symptoms seen in MS restrict the patient's daily activity and social role participation. Mobility problems and fatigue are the most important reasons of role limitations and decreased quality of life. The importance of exercise training in disease management has been emphasized in recent years. However, few studies have investigated the effects of task-oriented trainings on symptoms of the disease. The aim of this sudy is to investigate the effects of task-oriented training additional to combined exercise training on functional capacity, mobility, balance, fatigue and quality of life in patients with MS.

Enrollment: 34 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Multiple Sclerosis diagnosis
• Expanded Disability Status Scale > 5,5
• No cognitive problems
• No relapses in the last 3 months
• No other neurological or chronic disease

Exclusion criteria

• Relapse during the intervention
• Exercise intolerance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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34 participants in 2 patient groups

Control group

Active Comparator group

Description:

Patients in this group will receive combined exercise training included aerobic and strengthening exercises, 3 times a week for 6 weeks. All exercise sessions will be performed under the supervision of a physiotherapist.

Treatment:

Other: Combined exercise training

Training group

Experimental group

Description:

Patients in this group will receive task-oriented training additional to combined exercise training 3 times a week for 6 weeks. Task-oriented training included more functional daily life mobility activities like reaching, obstacle walking, stairs climbing. All exercise sessions will be performed under the supervision of a physiotherapist.

Treatment:

Other: Task-oriented training