Effects of Tea Catechin Extracts on Oxidative Damage

University of Shizuoka

Status

Completed

Conditions

Healthy

Treatments

Dietary Supplement: catechin extracts

Study type

Interventional

Funder types

Other

Identifiers

NCT00448513

CT2006005

Details and patient eligibility

About

The purpose of this study is to clarify the effects of tea catechin extracts on the frequency changes of micronuclei in peripheral lymphocytes compared with other oxidative stress markers in late middle aged healthy volunteers

Full description

Experimental studies have revealed that tea catechin extracts induce preventive effects on oxidative stress, but there have been few clinical trials conducted to verify the effects. Also, there have been few clinical markers indicating oxidative damage, and therefore, more accurate and reliable markers have been expected. The study is designed for evaluating the effects of tea catechin extracts on the frequency changes of micronuclei in peripheral lymphocytes as the indicator of oxidative damage, compared with other oxidative stress markers in late middle aged healthy volunteers.

Enrollment

40 patients

Sex

All

Ages

40 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

aged 40 to 65 years old
healthy volunteers
obtained written informed concent before participation

Exclusion criteria

participant who is not able to refrain from drinking tea for 2 weeks during the study
participant taking supplements or herbal products including folate, vitamin B, C, E, coenzyme Q10, calcium, for 2 weeks before the study
participant taking supplements or herbal products including folate, vitamin E for 3 months before the study
participant possessing tea allergy