Effects of The Effects of Dietary Oils on Fasting Lipoprotein Lipids

ACH Food Companies

Status: Completed

Conditions: Hypercholesterolemia

Treatments: Other: Corn oil; Other: Olive oil

Study type: Interventional

Funder types: Industry

Identifiers

NCT01925716

PRV-1303

Details and patient eligibility

About

The objectives of this clinical trial are to assess the effects of dietary oils on blood lipids and other aspects of the fasting lipoprotein profile in healthy men and women with elevated cholesterol

Enrollment: 57 patients

Sex: All

Ages: 18 to 74 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fasting LDL-C level equal to or greater than 130 mg/dL and less than 200 mg/dL at visit 1
• Fasting triglycerides less than or equal to 350 mg/dL at visit 1

Exclusion criteria

• Has coronary heart disease or coronary heart disease risk risk equivalent, such as diabetes, atherosclerosis, etc
• Taking lipid medications intended to alter the lipids profile, including but not limited to statins, bile acid sequestrants, etc.
• Uncontrolled hypertension (systolic greater than or equal to 160 mm Hg or diastolic greater than or equal to 100 mm Hg)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

---

57 participants in 2 patient groups

Corn oil/olive oil

Experimental group

Description:

Corn oil 56 g per day for 21 days followed by olive oil 56 g for 21 days

Treatment:

Other: Corn oil

Other: Olive oil

Olive Oil/Corn Oil

Experimental group

Description:

olive oil, 56g per day for 21 days followed by corn oil, 56 g for 21 days

Treatment:

Other: Corn oil

Other: Olive oil