Effects of the Sugar Sucrose on Bodyweight and Energy Intake Over 28 Days in Obese Women

University of Hull

Status: Completed

Conditions: Obesity

Treatments: Dietary Supplement: Aspartame; Dietary Supplement: Sucrose

Study type: Interventional

Funder types: Other

Identifiers

NCT01799096

MRRH003

Details and patient eligibility

About

This study partially replicates two previous studies with normal weight women, and overweight women. Both found that women could compensate for sucrose added to the diet in carbonated soft drinks (4 x250ml total1800 kJ per day) when it was given blind over a period of 4 weeks. The hypothesis is that this applies also to obese women, who will not gain weight, increase overall energy intake in the diet, or eat differently whilst consuming sucrose. 42 participants shall be randomly assigned to either be given carbonated drinks that contain sucrose, or drinks that are artificially sweetened.

Enrollment: 41 patients

Sex: Female

Ages: 20 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female
• BMI 30-35 kg/m²
• at least one period of dietary restriction of 4 weeks or more in the last 24 months

Exclusion criteria

• dislike of popular sweet carbonated drinks
• dieting during the last month
• history of diabetes
• having an eating disorder
• depression,
• being a smoker
• pregnant
• lactating,
• wearing a pacemaker
• currently taking medication for mood or thyroid disorders

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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41 participants in 2 patient groups, including a placebo group

Sucrose

Experimental group

Description:

Receives sucrose

Treatment:

Dietary Supplement: Sucrose

Aspartame

Placebo Comparator group

Description:

Receives Aspartame sweetened drinks

Treatment:

Dietary Supplement: Aspartame