Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery

Rio de Janeiro State University

Status: Completed

Conditions: Fibrin/Therapeutic Use; Bone Regeneration; Blood Platelets; Molar, Third

Treatments: Procedure: Control group; Procedure: Platelet-rich fibrin

Study type: Interventional

Funder types: Other

Identifiers

NCT02890680

CAAE 56621216.5.0000.5259

Details and patient eligibility

About

The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.

Enrollment: 20 patients

Sex: All

Ages: 16 to 29 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy patients
• Preoperative platelet count higher than 150,00/ mm3
• Patient who required bilateral mandibular third molar extractions

Exclusion criteria

• Smokers patients
• Alcoholics patients
• Patients whom the inferior second molar was missing
• Patients who had acute pericoronitis on the inferior third molar
• Severe periodontal disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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20 participants in 2 patient groups, including a placebo group

Platelet-rich fibrin group

Experimental group

Description:

Use platelet-rich fibrin after mandibular third molar extraction

Treatment:

Procedure: Platelet-rich fibrin

Control group

Placebo Comparator group

Description:

mandibular third molar extraction

Treatment:

Procedure: Control group