Effects of Three Different Mouth Rinses on Dental Plaque in Children

Suez Canal University

Status: Completed

Conditions: Gingival Diseases

Treatments: Other: Distilled water; Drug: pomegranate peel aqueous extrac; Drug: guava leaves aqueous extract; Drug: sodium fluoride solution

Study type: Interventional

Funder types: Other

Identifiers

NCT06013735

241/2019

Details and patient eligibility

About

Dental plaque is a major problem in the field of oral and dental health and its prevention is more important to avoid dental caries and gingival diseases. Mouth washes are very useful in the reduction of microbial plaque and gingival inflammation. Sodium fluoride mouth wash is one of the ways that prevent dental plaque. Recently, using herbal products are efficient in decreasing dental plaque. Pomegranate peels and Guava leaves extracts are an essential medicinal plant with various pharmacological properties.

Aim of study: To evaluate and compare the efficiency of different mouth rinses (sodium fluoride mouth rinse, guava leaves aqueous extract and pomegranate aqueous extract) on dental plaque in children, clinically by measuring gingival and plaque indices scores and microbiologically by measuring of streptococcus mutans and lactobacillus.

Materials and methods: forty apparently healthy and cooperative children were selected from the Outpatient Dental Clinic of Pediatric dentistry Department, Faculty of Dentistry, Suez Canal University. Children were randomly divided into three groups as follows:

Group (I):10 children will rinse with sodium fluoride, Group (II): 10 children will rinse with guava leaves aqueous extract and Group (III):10 children will rinse with pomegranate peels aqueous extract. Group (IV):10 children will rinse with water (control group). Instructions for oral hygiene and using mouth wash will be demonstrated for every child. Clinical and microbiological examinations will be done firstly at day one before using any type of examined mouthwashes (0-base line), then clinical and microbiological follow up will be done after 7 and 15 days of using different mouthwash for each group.

Enrollment: 40 patients

Sex: All

Ages: 6 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Children are apparently healthy.
2. Their age's ranges from 6-12 years {mixed dentition}, First permanent molars were fully erupted.
3. Children are not taking antibiotics, steroids and inflammatory therapy for two weeks before study or during this study.
4. Children are caries free at time of the study.
5. Children with no regular use of chewing xylitol gum.
6. Children without orthodontic appliance.
7. Children are not using fluoride tooth paste or any topical fluoride application at time of study.
8. Children who have dental plaque.

Exclusion criteria

1. Uncooperative children.
2. Children with history of allergy to dental products or their products
3. Parents refusal.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 4 patient groups, including a placebo group

sodium fluoride solution

Active Comparator group

Description:

children will rinse with sodium fluoride solution mouth rinse (0.2%).

Treatment:

Drug: sodium fluoride solution

guava leaves

Active Comparator group

Description:

children will rinse with guava leaves aqueous extract mouth rinse (0.5%).

Treatment:

Drug: guava leaves aqueous extract

pomegranate peel

Active Comparator group

Description:

children will rinse with pomegranate peel aqueous extract mouth rinse (0.5%).

Treatment:

Drug: pomegranate peel aqueous extrac

Control

Placebo Comparator group

Description:

children will rinse with distilled water

Treatment:

Other: Distilled water