Effects of Time of Day and Nut Intake on Cognitive Performance

Monash University

Status: Completed

Conditions: Cognitive Performance

Treatments: Other: Nut-free meal; Other: Nuts

Study type: Interventional

Funder types: Other

Identifiers

NCT06343142

Nuts for thought

Details and patient eligibility

About

This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.

Full description

In this trial, eligible participants will receive isocaloric meals with or without nuts at lunchtime and dinner time. Cognitive performance will be performed before and 90 min after the meals.

Enrollment: 22 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Non-shift workers
• 18-55 years
• BMI between 18.5 and 27 kg/m2,
• Non-smokers
• Without chronic illnesses

Exclusion criteria

• Allergy to nuts
• BMI<18.5 or >27 kg/m2
• Presence of dementia or psychiatric disease (depression, Parkinson's disease, schizophrenia)
• Presence of diabetes, serious health conditions that may affect participation e.g. liver or thyroid dysfunction, recent major surgery, cardiovascular disease
• Presence of any sleep disorders
• Taking anti-diabetic or lipid-lowering medication
• Do not speak English
• Pregnant or planning on becoming pregnant
• Breastfeeding

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

22 participants in 4 patient groups, including a placebo group

Lunch nut-free meal

Placebo Comparator group

Description:

Participants will receive an isocaloric meal without nuts at lunchtime.

Treatment:

Other: Nut-free meal

Lunch nut meal

Experimental group

Description:

Participants will receive an isocaloric meal with nuts at lunchtime.

Treatment:

Other: Nuts

Dinner nut-free meal

Placebo Comparator group

Description:

Participants will receive an isocaloric meal without nuts at dinner.

Treatment:

Other: Nut-free meal

Dinner nut meal

Experimental group

Description:

Participants will receive an isocaloric meal with nuts at dinner.

Treatment:

Other: Nuts