Effects of Tourniquet Applied During Total Knee Replacement Surgery on Patient Hemodynamics and Blood Table

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Status: Completed

Conditions: Primary Gonarthrosis

Treatments: Procedure: Total knee replacement

Study type: Observational

Funder types: Other

Identifiers

NCT07002086

67926

Details and patient eligibility

About

This study was planned to investigate the physiopathology of bradycardia and hypotension that occur in some patients with total knee arthroplasty (TKA) between the ages of 65 and 90 years when the tourniquet, which is routinely used in patients with total knee arthroplasty (TKA), is opened at the end of the operation and to determine the physiopathology of these effects of the tourniquet and how these effects can be prevented.

Full description

This study was planned to investigate the effects of lower extremity tourniquets routinely used in TDP surgeries on hemodynamics, SpO2, ETCO2 and blood tables in male and female patients aged 65-90 years. In the patients included in the study, measurements from the monitor will be recorded and preop and postop hemogram, complete biochemistry, coagulation arterial blood gases will be recorded from each patient's file and the values before and after the tourniquet will be compared. New randomized prospective studies will be proposed by determining the physiopathological changes (reperfusion syndrome) that occur after opening the tourniquet in patients and evaluating how these changes can be prevented

Enrollment: 22 patients

Sex: All

Ages: 65 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA score: 1-3
• primary gonarthrosis

Exclusion criteria

• ASA score 4 and above
• The diagnosis of secondary gonarthrosis
• Concomitant rheumatological disorders
• Concomitant peripheral vascular disease
• Concomitant malignant disease
• Presence of organ failure
• Having active infection
• Use of immunosuppressive drugs
• Having addiction to cigarettes, alcohol or drugs
• Use of anticoagulation medicine
• Presence of metabolic disease
• Presence of renal disease
• Presence of familial hemophagocytic syndrome
• Being unwilling to participate the study