Effects of Transcranial Direct Current Stimulation on Glucose Level

Riphah International University

Status: Completed

Conditions: Glucose Metabolism Disorders

Treatments: Other: Sham tDCS; Device: tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT06479590

REC01893 Faryal Shoukat

Details and patient eligibility

About

Previous studies have investigated the impact of tDCS on systemic glucose, neglecting to explore its effects on diabetic factors and its safety. Some studies used small sample size, limiting the ability to identify significant impacts or generalized findings to large population.

Full description

The proposed study suggests addressing these gaps by employing a large sample size, comprehensive outcome measurements, assessing tDCS impact on diabetes mellitus (DM) risk variables, and integrating ethical considerations into the research design and implementation. The study aims to fill existing gaps in knowledge about tDCS effects on blood glucose regulation and diabetic risk factors by conducting more robust research methodologies The effects of tDCS on addictive behavior and cerebral glucose metabolism in problematic online gamers were examined in a single-blinded RCT. Over a 4-weekperiod, participants received 12 sessions of either active or sham tDCS to the dorsolateral prefrontal cortex. In the active group, glucose metabolism was enhanced in certain brain regions, showing decreased addiction severity in both groups. As a result of these findings, it appears that prefrontal tDCS is capable of controlling gaming behaviors and enhancing cerebral glucose metabolism

Enrollment: 50 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Both Male & Female
• Age 18-30 years

Exclusion criteria

• Pregnancy
• Lactating mothers
• Skin Irritation and Allergies
• Brain Tumor or Shunt
• Brain Metallic implants
• Epileptic disease
• GI Disorder and Endocrine Disorder
• Drug abuse
• History of medications any hormonal therapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

50 participants in 2 patient groups

tDCS Group

Experimental group

Treatment:

Device: tDCS

Sham Group

Sham Comparator group

Treatment:

Other: Sham tDCS