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Effects of Transcranial Direct Current Stimulation on Postural Control

U

Universidade Federal do Piauí

Status and phase

Completed
Phase 3
Phase 2

Conditions

Parkinson Disease

Treatments

Procedure: Transcranial direct current stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT03759132
tDCS in Parkinson's Disease

Details and patient eligibility

About

Parkinson's disease is a progressive, degenerative neurological disease associated with profound changes in the quality of life of its survivors. Recent evidence has demonstrated the potential use of transcranial direct current stimulation (tDCS) to modulate cerebral excitability and movement control in neurological chronic conditions. However, few studies have investigated the effects of tDCS on postural control in patients with Parkinson's disease. This study aims to investigate the effect of bihemispheric tDCS on postural control in people with Parkinson's disease. Participants will be randomized to receive a single session of anodal and sham bihemispheric tDCS (7 days between each type of stimulation).

Primary clinical outcome (balance) will be collected before and immediately after tDCS. The data will be collected by a blind examiner to the treatment allocation.

Enrollment

18 patients

Sex

All

Ages

40 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Medical diagnosis of idiopathic Parkinson's disease present for at least 12 months

In clinical follow-up and pharmacological treatment by a responsible physician

Parkinson's classification of 1.5-3 according to the Hoehn and Yahr scale

Signing of the free and informed consent form-

Exclusion criteria

Use any associated orthopedic device to aid gait or balance control

Signs of severe dementia (evaluated by the Mini-Mental State Examination - MMSE)

Diagnosis of other neurological disorders (including those of central and peripheral nature)

Previous treatment with tDCS

Medical diagnosis of psychiatric illnesses with the use of centrally acting medications (depressants)

The use of pacemakers or other implanted devices.-

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

18 participants in 2 patient groups

Anodal tDCS
Experimental group
Description:
Bihemispheric tDCS applied over primary motor cortex. Dose: 2mA, 20 minutes
Treatment:
Procedure: Transcranial direct current stimulation
Sham tDCS
Sham Comparator group
Description:
Bihemispheric tDCS applied over primary motor cortex. Dose: 2mA, 20 minutes (30s ON)
Treatment:
Procedure: Transcranial direct current stimulation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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