Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery

Qing Yuan

Status: Completed

Conditions: Postoperative Pain After Cesarean Section

Treatments: Drug: The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)

Study type: Interventional

Funder types: Other

Identifiers

NCT07478692

202318001040

Details and patient eligibility

About

ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial

Enrollment: 83 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged 20-40 years, in good general health
• ASA physical status I-II
• Singleton, term (37-41 weeks) pregnancy with normal fetal development
• Planned for elective cesarean section, no labor

Exclusion criteria

• Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption)
• Major organ dysfunction (heart, liver, kidney) or psychiatric history
• Allergy to local anesthetics or any study drugs
• Prior abdominal surgery or infection that may affect block efficacy
• Coagulation disorders or current anticoagulant use
• Refusal to participate or inability to comply with follow-up

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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83 participants in 2 patient groups

TAP Block Group

Experimental group

Description:

The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg + tropisetron 8 mg);

Treatment:

Drug: The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)

the control group

No Intervention group

Description:

received only the same formula intravenous analgesia pump. For both groups, rescue