Effects of Using E-Cigarettes on Lungs in People With HIV (HBS Ancillary)

Pennington Biomedical Research Center

Status

Completed

Conditions

Lung Injury

Hiv

Study type

Observational

Funder types

Other

NIH

Identifiers

NCT04794543

PBRC 2020-028

U54GM104940 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This is an ancillary study, thus participants will be recruited from participants in the HBS Study. This project acutely assesses the role of the e-cigarettes and vaping on lung health. The proposed work will inform the design of future studies to better understand vaping's health consequences and to test novel interventions to mitigate vaping's contribution to acute and/or chronic lung injury.

Enrollment

23 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

This project is an ancillary study to the HBS Study. Inclusion Criteria for that IRB approved study are:

documented HIV-infection
in care at an HIV specialty clinic
age ≥ 18 years.

Exclusion criteria for the HBS Study are:

a pacemaker or other implanted electronic device
pregnant women, prisoners, cognitively-impaired subjects.

For this ancillary, the experimental group must actively use at least one of the following: e-cigarettes, e-liquid vapes, burning leaf tobacco cigarettes, or inhaled burning leaf marijuana (cannabis). The control group will have no use of e-cigarettes or vape or active smoking in the past year.

Participants must be willing to archive data and biological samples for future use.

Exclusion from the ancillary are:

overt respiratory or oral cavity disease
acute illness in the past 4 weeks
active cancer
active weight loss program
any other medical, psychiatric or behavioral factors that, in the judgment of the PI may interfere with study participation or ability to follow the protocol