Effects of Viscous Fibre Containing Foods on Satiety (Gel Form)

Unity Health Toronto

Status and phase: Unknown; Phase 1

Conditions: Obesity

Treatments: Dietary Supplement: Konjac Glucomannan

Study type: Interventional

Funder types: Other

Identifiers

NCT02134938

KJM-G

Details and patient eligibility

About

The purpose of this study is to assess whether low caloric, low energy density, konjac food products are effective in appetite regulation when administered as caloric replacements. It is hypothesized that replacement of typical, balanced, vegetarian meals with konjac food products will have comparable satiety scores, decreased postprandial glucose response, and will not significantly affect subsequent food intake.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy, non-smoking males and females
• Aged 18-70 years
• BMI between 18 - 29.9 kg/m²
• Non-dieters (1-10 score on Stunkard Eating Inventory)

Exclusion criteria

• Known reported history of liver or kidney disease, diabetes, hypertension, stroke or myocardial infarctions, thyroid disease, Celiac disease/gastrointestinal disease, or AIDS
• Weight change of +/- 3kg in the last 2 months
• Alcohol intake >2 drinks/day
• Inability to consume KJM-G meals
• Any condition which might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results
• Non-compliance with experimental procedures or safety guidelines

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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20 participants in 3 patient groups

Konjac Glucomannan

Experimental group

Description:

650g KJM-G

Treatment:

Dietary Supplement: Konjac Glucomannan

Half Control/Half Konjac Glucomannan

Experimental group

Description:

325g KJM-G

Treatment:

Dietary Supplement: Konjac Glucomannan

Control

No Intervention group

Description:

0g KJM-G