Effects of Vitamin D Supplementation on Postoperative Rehabilitation in Hip and Knee Osteoarthritis Patients
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About
The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty. The main questions it aims to answer are:
Does oral vitamin D supplementation for a period of time after joint arthroplasty affect the postoperative recovery speed in patients who have vitamin D deficiency? Does oral vitamin D supplementation after joint arthroplasty affect the long-term recovery of joint functions in patients who have vitamin D deficiency?
Participants will:
Take vitamin D oral supplement every day for 3 months. Visit the clinic in 1, 3, 6, 12 months after joint replacement surgery for checkups and tests.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Vitamin D deficiency (blood 25-hydroxyvitamin D value < 20ng/ml);
- Meeting the diagnostic criteria for hip or knee osteoarthritis;
- Planning to undergo hip or knee arthroplasty after clinical assessment;
Exclusion criteria
- Having other diseases that could cause damage to the bone or cartilage structure of the hip or knee, such as trauma, joint infection, congenital joint malformation, and systemic diseases such as rheumatoid arthritis and gout.
Trial design
Primary purpose
Allocation
Interventional model
Masking
300 participants in 2 patient groups
Trial contacts and locations
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Central trial contact
Zihao Qu, MD; Xiang Zhao, MD
Data sourced from clinicaltrials.gov
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