Effects Of Walnut-Enriched Diet On Blood Lipids And Glucose Profiles In Hyperlipidemic Subjects

Eastern Mediterranean University

Status: Completed

Conditions: Hyperlipidemias

Treatments: Dietary Supplement: Walnut-enriched Group

Study type: Interventional

Funder types: Other

Identifiers

NCT03680027

2015/13-04

Details and patient eligibility

About

Walnuts have been shown to reduce serum lipids in hyperlipidemic individuals with a well-controlled feeding trials. Current study have been determined the effects of daily walnut consumption on serum lipids, fasting glucose and insulin levels in hyperlipidemic individuals.

Full description

In this, randomized controlled trial, mild to moderate hyperlipidemic subjects were randomly divided into 2 groups as walnut-enriched (n=20) and control (n=17) groups for 6 weeks. All subjects adhered to a medical nutrition therapy as low-fat and low-cholesterol diet. The walnut-enriched group was supplemented with 40 g/day of walnuts added to their diets. In order to follow nutritional status of subjects, they were visited every 15 days (in total 4 times). Anthropometric measurements of the subjects were taken and were monitored at each visit during the study. Blood samples were measured at the beginning and again at the end of the study.

Enrollment: 37 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hyperlipidemic patients who are not using any lipid lowering medications
• Non-smoker
• No alcohol consumption
• Individuals who are having ≤30kg/m2
• Individuals who do not have any allergy for nut consumption
• Female participants who are not pregnant or breastfeeding
• Individuals should not be in a weight loss programme
• Having not consumed regular nuts for the last 1 month,
• Except hypertension, they should not have other chronic diseases (such as diabetes, chronic renal failure)
• No intense exercise

Exclusion criteria

• Failure to meet the criteria for inclusion criteria.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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37 participants in 2 patient groups

Control Group

No Intervention group

Description:

In 'Control group' participants had 6 week follow-up without any intervention.

Interventional Group

Experimental group

Description:

In 'Interventional group' participants had 6 week follow-up and during that period of time, they were asked to consume 40g/day walnut. Participants in intervention group was ensured to consume all 40g of walnut every day, during their snack times for 6 weeks.

Treatment:

Dietary Supplement: Walnut-enriched Group