Effects of WB-EMS and Dietetic Treatment on Cancer Patients

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Weight Loss; Muscle Weakness; Cancer Cachexia; Cancer; Muscle Loss

Treatments: Other: Whole-Body Electromyostimulation (WB-EMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT02293239

EMS Tumor 01

Details and patient eligibility

About

This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function and quality of life of patients with malignant disease undergoing curative or palliative anti-cancer treatment

Enrollment: 278 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• malignant disease (solid or hematological cancer): head and neck cancer, colorectal carcinoma, small intestinal cancer, gastric cancer, oesophageal cancer, pancreas carcinoma, liver cell carcinoma, cholangiocarcinoma,lung cancer, breast cancer, cervix cancer, ovarian cancer, prostate cancer, renal cell carcinoma, malignant melanoma, patients with leukaemia and malignant lymphomas or Graft-versus-Host-Disease after bone marrow transplantation
• ongoing or planned curative or palliative anti-cancer therapy

Exclusion criteria

• simultaneous participation in other nutritional or exercise intervention trials
• acute cardiovascular events
• use of anabolic medications
• epilepsy
• severe neurological diseases
• skin lesions in the area of electrodes
• energy active metals in body
• pregnancy
• acute vein thrombosis

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

---

278 participants in 2 patient groups

Control Group

No Intervention group

Description:

"usual care" control group receives individualized nutritional support (dietary advices: daily protein intake \> 1.0 g/kg bodyweight)

WB-EMS group

Experimental group

Description:

physical exercise group regular WB-EMS training (2 EMS trainings per week; each session for 20 min) + individualized nutritional support (dietary advices: daily protein intake \> 1.0 g/kg bodyweight)

Treatment:

Other: Whole-Body Electromyostimulation (WB-EMS)