Effects of WB-EMS and Protein Supplementation on LBM Maintenance During Intended Weight Loss

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Overweight; Abdominal Obesity; Obesity

Treatments: Behavioral: WB-EMS application; Dietary Supplement: Protein; Behavioral: Walking

Study type: Interventional

Funder types: Other

Identifiers

NCT03746977

WREPP

Details and patient eligibility

About

The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women. Three study groups were implemented: (1) Protein supplementation (only) group (2) Protein supplementation and walking intervention (3) Protein supplementation, walking and WB-EMS-application. All protocols were applied for 16 week of intervention.

A energy deficit of 500 kcal/d was intended however while group (1) focus consistently on energy restriction (500 kcal/d), in group (2) and (3) a combined physical activity (i.e. walking with a volume representing 250 kcal/d) and energy restriction (250 kcal/d) protocol was applied. Total protein uptake including protein supplementation was calculated to average around 1.2 g/kg body mass per day in groups (1) and 1.5 g/kg body mass/d in group (2) and (3). WB-EMS was applied 1.5x 20 min/week (i.e. each Tuesday and every second Thursday).

Primary study endpoint was LBM as determined by Dual Energy x-Ray Absorptiometry.

Enrollment: 30 patients

Sex: Female

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• premenopausal women 25-50 years old
• overweight/obesity (body fat rate equal or higher 30%)

Exclusion criteria

• medication and diseases affecting muscle and fat metabolism
• pregnant or parturition < 6 months
• any condition or medication that prevent proper physical activity or WB-EMS application
• holidays equal or more than 1 week during the intervention period
• other interventions with impact on the primary and core secondary outcome (i.e. body fat parameters) started during the last year.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 3 patient groups

energy restriction and protein supplementation

Active Comparator group

Description:

Energy restriction of 500 kcal/d and total Protein Uptake (including Supplementation) of 1.2 g/kg body mass/d

Treatment:

Dietary Supplement: Protein

Energy restriction, walking and protein

Active Comparator group

Description:

Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d) and total protein uptake (including supplementation) of 1.5 g/kg body mass/d

Treatment:

Behavioral: Walking

Dietary Supplement: Protein

Energy restriction, walking, protein and WB-EMS

Active Comparator group

Description:

Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d), total protein uptake (including supplementation) of 1.5 g/kg body mass/d and WB-EMS application 1,5x 20 min/week

Treatment:

Behavioral: Walking

Behavioral: WB-EMS application

Dietary Supplement: Protein