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Effects of Whey Protein and Collagen Supplementation

U

Universidade Norte do Paraná

Status

Completed

Conditions

Muscle Strength
Resistance Training
Nutrition Therapy
Exercise
Hypertrophy

Treatments

Dietary Supplement: Whey protein supplementation
Dietary Supplement: Collagen supplementation

Study type

Interventional

Funder types

Other

Identifiers

NCT04213586
3.058.958

Details and patient eligibility

About

The present project aims to investigate the effects of high-quality protein (whey protein) vs. low-quality protein (collagen) on muscle mass and function (e.g., strength and power) during a 10-wk resistance training program in young adults. It will be tested the hypothesis that leucine-matched collagen should promote similar gains on muscle function and mass compared to whey protein supplementation.

Full description

The purpose of this study will be to investigate the effects of whey protein vs. leucine-matched collagen supplementation on muscle mass and function after a 10-wk resistance training program. Initially, all participants will be submitted for a 2-wk familiarization period, and then randomized into two groups (N = 11 / group): whey protein group and leucine-matched collagen group. The following variables will be assessed from pre-to post-training: anthropometric, muscle thickness from vastus lateralis and biceps brachii muscles using ultrasound, training load, mean power and peak torque for unilateral arm flexion exercise using a isokinetic dynamometer, countermovement vertical jump, nutritional intake, and testosterone-to-cortisol ratio . Shapiro-Wilk and Levine tests will be used to test the normality and homogeneity of the measurements, respectively. Two-way ANOVA (group x time) tests for repeated measures will be performed to assess changes over time and between groups for all dependent variables. Violation of sphericity will adjust using Greenhouse- Geyser correction. The Bonferroni post-hoc test will detect specific differences between groups. When appropriate, the percentage of change (∆%) will be reported according to the following equation: ∆% = [(pre-average post average) / pre-average mean] × 100. Values will be express as mean ± standard deviation. O significance level α will be 0.05.

Enrollment

22 patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Men and women aged 18-35 years
  • To be eutrophic (not overweight or obese)

Exclusion criteria

  • To present a history of musculoskeletal disorders
  • Be attending a systematized weight training program for at least six months
  • To make use of medicines that could affect muscle function.
  • To have used ergogenic supplements and anabolic steroids for at least six months before study
  • To have restrictions for exercises practice considering Physical Activity Readiness Questionnaire (PAR-Q) responses.

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

22 participants in 2 patient groups

Whey Protein
Experimental group
Description:
Each participant will be supplemented with whey protein (7 d/wk) during 10 weeks.
Treatment:
Dietary Supplement: Whey protein supplementation
Leucine-matched collagen
Experimental group
Description:
Each participant will be supplemented with collagen (7 d/wk) during 10 weeks.
Treatment:
Dietary Supplement: Collagen supplementation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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